Hookworm infection activates eosinophil‐mediated tissue inflammatory responses and involves the production of the eosinophil‐specific chemokine (eotaxin), recruitment of eosinophils, secretion of eosinophil cationic protein (ECP), and the secretion of anti‐parasite immunoglobulin E (IgE).6, 7. Here, IGHE is linked to ancylostomiasis.