Moreover, necroptosis-relevant risk score was negatively linked with CD8 T effector, and angiogenesis but was positively associated with pan-F-TBRS, FGFR3-related genes, EMT2, KEGG discovered histones, Fanconi anemia, cell cycle, cell cycle regulators, DNA replication, DNA damage repair, nucleotide excision repair, homologous recombination, and mismatch repair, indicative of the mechanisms underlying the necroptosis-relevant risk score. The gene discussed is FGFR3; the disease is Fanconi anemia.