↓IL-1β, ↓IL-6, ↓TNF-α; ↑SOD1,↑ SOD2, ↑GPX-1, ↑CAT; increase cell viability; Inhibit TLR4/NF-κB signaling pathway; improve dyskinesia and cognitive impairment. The gene discussed is TLR4; the disease is Cognitive impairment.