CTP significantly increased the levels of CD4 and CD8, enhanced the expression of IFN-γ, and suppressed the levels of IL-4 in the spleen (p < 0.05) (Figures 4A,C) and colorectal tumors (p < 0.05) (Figures 4B,D) of ApcMin/+ mice, suggesting the increased number of CD8+ and CD4+ cells and the increased proportion of helper T lymphocytes (Th)1/Th2 in CTP-treated ApcMin/+ mice. This evidence concerns the gene CD4 and colorectal neoplasm.