LRRTM1 and Anxiety: The region selective functions of LRRTM1 and LRRTM2 are further demonstrated by the lack of effect of Lrrtm1 and Lrrtm2 deletion in the dorsal hippocampus on social interaction or avoidance-related anxiety, which have been linked to the ventral hippocampus (Fanselow and Dong, 2010).