Pathogenetic variants in BRCA1 and BRCA2 genes (chromosome 17q21 and chromosome 13q12, respectively) predispose female carriers to an increased risk of breast, ovarian, and pancreatic cancer as well as melanoma [3, 4] and male carriers to an increased risk of breast and prostatic cancer [5]. Here, BRCA1 is linked to familial pancreatic carcinoma.