To examine the expression pattern of YTHDF2 in pan-cancer, we used the TIMER database analysis it’s expression pattern, the result demonstrated that YTHDF2 was significantly over-expression in BLCA, CHOL, COAD, ESCA, HNSC, KICH, KIRP, KIRC, LIHC, LUAD, PRAD, SKCM, STAD, THCA and UCEC (Figure 1A). The gene discussed is YTHDF2; the disease is cancer.