PROM1 and glioblastoma: Consequently, recent attempts to reduce the influence of the aforementioned variables (e.g., by excluding IDHmut tumors) reported successful characterization of SVZ GBM as a distinct gene-expression subtype with enrichment of cancer stem cell-like markers (e.g., CD133) and increased expression of genes associated with Notch and DNA-repair pathways [24, 45].