Indeed, we found marked elevations of CD40 ligand, granzyme B, IFN-α, IFN-γ, IL-2, IL-7 and CXCL10, especially in COVID-19 (ANOVA for overall between group differences P<0·05 and Games-Howell for post-hoc pairwise comparisons P<0·05, Figure 2a+b). This evidence concerns the gene CD40LG and COVID-19.