The multivariate logistic regression analyses using a forward stepwise model adjusted for age and gender (Table 3) showed that Hb < 13.5 g/dl (OR 5.85, 95% CI 2.17–15.75, p < 0.001) and SII ≥ 1820 (OR 4.78, 95% CI 1.44–15.85, p = 0.011) were independent risk factors for death within 1 year in advanced oropharyngeal cancer patients. The gene discussed is GSTM1; the disease is oropharynx cancer.