Specifically, the abundance of several ARGs belonging to aminoglycoside (aadA, aadE, ant(9)-I), bacitracin (bacA), MLS (ermA, ermB, ermG, lsa, macB), tetracycline (tet40), and vancomycin (vanG, vanS) (Fig. 4d) classes in KC were lower than in AN or CH. Here, HCCS is linked to keratoconus.