Yehia et al. assessed the relative expression of HIF-1α among three breast cancer groups (TNBC, HER2+, ER+/PR+), with TNBC expression results differed only slightly and with little to no statistical significance from the other subgroups, and that HER2 positive tumours showed the highest levels of expression for all studied parameters [29]. The gene discussed is PGR; the disease is breast carcinoma.