An immune-histochemical analysis has been conducted on 40 pancreatic cancer tissue samples, which has showed that at the invasive front of tumor, the expression of platelet marker CD42b was positively correlated with Snail expression (P = 0.02) and negatively correlated with E-cadherin expression (P = 0.008), indicating that extravasation platelets aggregation in the primary tumor is related to EMT formation [96]. This evidence concerns the gene CDH1 and neoplasm.