Several proteins that are involved in tumor vascularization were detected: histidine-rich glycoprotein (HRG), α-2-HS-glycoprotein, leucine-rich α-2-glycoprotein (LRG), secreted GRP78, macrophage migration inhibitory factor (MIF), VEGFA, and hepatoma-derived growth factor. This evidence concerns the gene LRG1 and neoplasm.