Multiple linear regression on α7nAChR staining levels incorporating age, parity, the menstrual phase at which the tissue sample was collected, and co-occurrence of uterine fibroids indicated that both OE and DE lesions were significantly associated with reduced α7nAChR staining (p = 0.0002 and p = 0.0009, respectively; R2 = 0.39). The gene discussed is CHRNA7; the disease is uterine corpus leiomyoma.