Among the four SNPs, rs79297227 with the lowest P value (1.01×10−7) located in SLC16A7 (12q14.1) showed a statistically suggestively significant interaction with the BMI trajectories, and the remaining three SNPs, including rs2336652 near CLASP2 (3p22.3, P = 3.92×10−7), rs16018 in CACNA1A (19p13.2, P = 3.92×10−7), and rs4726760 near BRAF (7q34, P = 9.19×10−7) interacted with the BMI trajectories in terms of the NSCLC risk. The gene discussed is SLC16A7; the disease is non-small cell lung carcinoma.