The expression levels of NLRP2, NLRP7, TNF, IL1B, IL6, and NLRP1 in GBM were downregulated relative to those in normal tissues, whereas the expression levels of PLCG1, CASP9, CHMP6, SCAF11, and CHMP4A were upregulated. The gene discussed is PLCG1; the disease is glioblastoma.