Tumor‐associated macrophages (TAMs) are protumoral in nature and are involved in tumor initiation, progression, immune regulation, metastasis, and angiogenesis by the secretion of various antiinflammatory cytokines such as IL‐10, IL‐13, IL‐4, surface expression of arginase‐1, mannose receptor (MR, CD206), and scavenger receptors [8]. The gene discussed is IL4; the disease is neoplasm.