ILC2-deficient mice had a substantial decrease in tumor numbers and size (Fig. 3A), and a significant (P < 0.0001) increase in life-expectancy compared to Cre-control (Rora+/+Il7rCre/+Apc1322T/+ or Rora+/fIl7rCre/+Apc1322T/+) mice (Fig. 3B and fig. This evidence concerns the gene RORA and neoplasm.