Hardy–Weinberg equilibrium was observed in both cases and controls and for all variants: LOC387715 (rs10490924) in AMD patients (p = 0.499) and controls (p = 0.203); CFH (rs1061170) in AMD patients (p = 0.948) and controls (p = 0.847); and HTRA1 (rs11200638) in AMD patients (p = 0.986) and controls (p = 0.515). The gene discussed is HTRA1; the disease is age-related macular degeneration.