In contrast, TnfKO and IfngKO CD4+ T cells blocked PyMtOvatg TslprKO breast tumor growth and induced the differentiation of the high-grade donor tumors into low-grade fibrocystic structures in Tslptg TslprKO mice (Fig. 6, B and C; and Fig. S3, H–J). The gene discussed is CD4; the disease is breast neoplasm.