CRP and Decreased total monocyte count: Nevertheless, since the proportion of patients with abnormalities varied greatly for individual parameters (from 40% for monocytopenia to 88% for leukopoenia) and since the levels of GGT and CRP were more often abnormal in the second phase whereas other parameters were abnormal in the initial phase of TBE, the pathogenic mechanisms leading to abnormalities are likely not uniform (the same).