Comparison of laboratory findings in the initial and the second (meningoencephalitic) phase of TBE revealed significant differences in peripheral blood leukocyte counts (including neutrophil, lymphocyte, and monocyte counts) and platelet counts, as well as serum concentrations of CRP, AST, and GGT but not for ALT (Table 1). This evidence concerns the gene CRP and tick-borne encephalitis.