In another example, Kang et al. achieved dosage-sensitive sex reversal, adrenal hypoplasia critical region, on chromosome X, gene 1 (DAX1) knockout in the monkey, which could recapitulate the phenotypes of human adrenal hypoplasia congenita (AHC) and hypogonadotropic hypogonadism (HH). Here, NR0B1 is linked to alternating hemiplegia of childhood.