By univariate and multivariate regression analysis, tumor max diameter [HR = 1.795 (1.152–2.798)], AFP [HR = 1.955 (1.294–2.955)], ALP [HR = 2.584 (1.488–4.486)], and different treatment modalities were prognostic factors for BCLC stage 0/A rHCC patients. Here, AFP is linked to neoplasm.