In a Cox proportional hazards regression analysis, tumor depth, SCC-Ag, and BRAT1-Ab were the explanatory variables and gender, age, location, lymph node metastasis, p53-Abs level, WBC, neutrophils, lymphocytes, hemoglobin, platelets, CRP, and albumin were tested (Table 5). This evidence concerns the gene TP53 and metastatic malignant neoplasm in the lymph nodes.