From Table 3, it can be seen that the detailed pathways contain the following: pathways in cancer, fluid shear stress and atherosclerosis, AGE-RAGE signaling pathway in diabetic complications, hepatitis B, prostate cancer, TNF signal pathway, IL-17 signaling pathway, bladder cancer, small-cell lung cancer, pancreatic cancer, Kaposi sarcoma-associated herpesvirus infection, human cytomegalovirus infection, non-small-cell lung cancer, HIF-1α signaling pathway, microRNAs in cancer, endocrine resistance, colorectal cancer, proteoglycans in cancer, apoptosis, and PI3K-Akt signaling pathway. The gene discussed is HIF1A; the disease is atherosclerosis.