SETDB1 and rectum adenocarcinoma: In the TIMER database, the SETDB1 expression level was elevated in bladder urothelial carcinoma (BLCA), BRCA, CHOL, colon adenocarcinoma (COAD), esophageal carcinoma (ESCA), GBM, HNSC, KIRC, LIHC, LUAD, lung squamous cell carcinoma (LUSC), rectum adenocarcinoma (READ), stomach adenocarcinoma (STAD), thyroid carcinoma (THCA), and uterine corpus endometrial carcinoma (UCEC) (Figure 4(a)).