NRL and central areolar choroidal dystrophy: Perturbations in the transcription factors ONECUT2 (One Cut Homeobox 2), EGR1 (Early Growth Response 1), NRL (Neural Retina Leucine Zipper), and VAX2 (Ventral Anterior Homeobox 2) seems to affect the expression of the genes found in association with CACD in this review, all based in knockout assays in mouse (Alfano et al., 2011; Goetz et al., 2014; Oh et al., 2017; Han et al., 2018; Corso-Díaz et al., 2020).