Elevated PPP1R14A expression indicated poor outcomes for the PFI of patients in ACC (p < 0.001), BRCA (p = 0.023), CESC (p < 0.001), COAD (p = 0.007), gliomas (p < 0.001), KIRP (p = 0.002), LUSC (p = 0.037), OV (p = 0.018), READ (p = 0.025), SKCM (p = 0.02), STAD (p = 0.007), TGCT (p = 0.011), and UCS (p = 0.041) and signaled a positive prognosis in LIHC (p = 0.037) and THCA (p = 0.027) (Figure 6). Here, PPP1R14A is linked to central nervous system cancer.