Downregulated PPP1R14A mRNA expression was observed in tumor tissues versus normal tissues in ACC, BLCA, BRCA, CESC, COAD, ESCA, GBM, HNSC, KICH, KIRC, KIRP, LAML, LGG, LUAD, LUSC, OV, PCPG, PRAD, READ, SKCM, STAD, TGCT, THCA, USEC, and UCS datasets, and the upregulated PPP1R14A expression profile was detected in CHOL, DLBC, HNSC, PAAD, and THYM datasets (Figure 1B). The gene discussed is PPP1R14A; the disease is adrenal cortex carcinoma.