EIF2AK3 and hereditary sensory and autonomic neuropathy: In addition, DRG expression levels of the phospho-activated mitogen-activated protein kinases (MAPKs) pERK (Figure 2E), pJNK (Figure 2F), and pp38 (Figure 2G) were elevated in CIP model mice, and these effects were reversed by AI and lower in Trpv1−/− mice than WT mice following CIP induction.