Inflammatory mediators are thought to cause severe inflammatory responses to tissue damage, and IL-6, IP-10 and MCP-1 have been found to be associated with acute lung injury and even poor prognosis and higher risk of death in SARS-CoV-1 (Jiang et al., 2005; Chien et al., 2006) and SARS-CoV-2 infections (Chen et al., 2020; Jøntvedt Jørgensen et al., 2020; Liu et al., 2020; Hashimoto et al., 2021). This evidence concerns the gene IL6 and injury.