Similarly, S100A8 significantly reduced percentages of total and M-MDSC in spleens from mice with LLC cancers (Total MDSC: 1.10 ± 0.15% to 0.62 ± 0.10%, p < 0.05; M-MDSC: 0.18 ± 0.04% to 0.07 ± 0.01%, p < 0.05); PMN-MDSC showed a trend of decrease (Figures 5J–L). This evidence concerns the gene S100A8 and cancer.