Moreover, recent researches have reflected that ferroptosis could facilitate renal damage in diabetic nephropathy (DN), and lipid peroxidation is increased in DN mice, and the expressions of ACSL4, SLC7A11, and SLC3A2 are up-regulated, while GPX4 is down-regulated (Wang Y. et al., 2020). Here, SLC3A2 is linked to liver dysplastic nodule.