SLC7A11 and renal fibrosis: In different models, artemisinin and its derivatives have been reported to induce ferroptosis by triggering ROS, promoting ferritin degradation, and regulating xCT/GPX4 axis (Louandre et al., 2013; Louandre et al., 2015; Sun et al., 2016), thus alleviating renal fibrosis (Cao et al., 2016; Zhang et al., 2017; Wen et al., 2019; Zhang et al., 2019; Liu et al., 2020).