Most of DEGs were overexpressed in COVID-19 patients compared to non-COVID-19 patients, including METTL3, METTL14, WTAP, VIRMA, ZC3H13, RBM15, CBLL1, YTHDC1, YTHDF3, HNRNPC, HNRNPA2B1, FMR1, ELAVL1, and FTO, and several DEGs, such as RBM15B, IGFBP2, and IGFBP3 were downregulated in COVID-19 patients. Here, METTL3 is linked to COVID-19.