Furthermore, DYRK1A and TSC1 were coexpressed in clinical tumour samples from patients with HCC (Spearman correlation analysis; r = 0.61, p < 9.4e–39; Pearson correlation analysis, r = 0.62, p < 0.0001; Fig. 5c) [32]. This evidence concerns the gene TSC1 and hepatocellular carcinoma.