ACE and obesity due to melanocortin 4 receptor deficiency: Also, an unhealthy dietary pattern with high amounts of saturated fat, refined carbohydrates and sugars, low levels of fiber, unsaturated fats and antioxidants are linked with inflammation, hyperglycemia, hyperlipidemia, obesity and chronic disease, which are risk factors related to high mortality in patients with severe COVID-19 infection; further, this dietary pattern increases ACE levels, the main entry point for coronavirus 2 into cells.