The research databases, TCGA (https://www.cancer.gov/tcga) and GEO, GSE6956, https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE6956 jointly revealed significant TM9SF4 overexpression in PCa and were closely associated with the poor prognosis of PCa patients (Fig. 5A-C). This evidence concerns the gene TM9SF4 and posterior cortical atrophy.