To confirm whether IL-39 affects B-cell response during cGVHD, we harvested splenocytes from recipients with scleroderma-like cGVHD and examined the expression of surface markers of B lymphocytes, including B220, Fas (CD95), GL-7, and CD138 in recipient mice on day 56 post allo-HSCT. The gene discussed is FAS; the disease is scleroderma.