First, in the TARGET, E-MTAB-161, E-MTAB-1781, E-MTAB-8248, E-TABM-38, GSE49710 and GSE85047 datasets, the expression levels of CCNE1 were higher in paediatric neuroblastoma patients with an age at diagnosis ≥ 18 months than in paediatric neuroblastoma patients with an age at diagnosis < 18 months (Fig. 6a). This evidence concerns the gene CCNE1 and neuroblastoma.