Integrated analysis of eight independent datasets, TARGET, E-MTAB-161, E-MTAB-1781, E-MTAB-8248, E-TABM-38, GSE16476, GSE49710 and GSE85047, suggested that TP53 and its associated genes CCNE1, CDK2, CHEK2 and SESN1 were significantly correlated with the clinical outcomes of paediatric neuroblastoma. Here, CHEK2 is linked to neuroblastoma.