For the present study, we received pTau and tTau concentrations of 88% of the CSF samples and compared sensitivity, specificity and AUC values for each biomarker alone and as combination of three biomarkers (for PD and DLB: pTau, tTau and aSyn aggregates, for AD and PSP: pTau, tTau and Tau aggregates). This evidence concerns the gene MAPT and supranuclear palsy, progressive, 1.