DSG1 and pemphigus: Antibody tests were not described in a substantial number of studies on pemphigus, but histopathologic diagnosis implicates the presence of the relevant IgG4 autoantibodies (mostly desmoglein 1 and desmoglein 3, < 0.5% of patients desmocollin), the inclusion criteria were changed during the second round of screening to include the pemphigus studies in the quantitative analysis.