Panel proteins of these two models have molecular functions linked to the immune system (C7, CFH, FCN2, ORM1), ECM organization, cell–cell adhesion and migration (TGFBI, LGALS3BP, QSOX1), coagulation cascade (F2, SERPINC1, PROC), transport in the bloodstream (TTR, ORM1 and APOF), metabolism (ALDOB) and HCC (prognostic markers CLEC3B, ASAP1). This evidence concerns the gene ORM1 and hepatocellular carcinoma.