TGFBI and Hepatic fibrosis: Among the top 20 proteins most correlated with stages of fibrosis were prominent liver-secreted proteins (Fig. 2d) with roles in cell–ECM interactions (TGFBI and EMILIN1 (ref. 44)), as well as those previously associated with hepatic fibrosis (IGFBP7 (ref. 45) and TNXB46).