COL1A1, COL1A2, ACTA2, PDGFRB and FAP displayed a significant positive correlation with this gene dataset in melanoma tumours (SKCM), whereas in pancreatic tumours (PAAD), that correlation was even stronger owing to their highly desmoplastic TME (Fig. 7a and Extended Data Fig. 9a). This evidence concerns the gene COL1A1 and pancreatic neoplasm.