For patients with papillary thyroid carcinoma, macrophages, mast cells, natural killer (NK) cells, Tfh cells, activated dendritic cells (aDCs), B cells, Tregs, CD8 + T cells and DCs were associated with LTF expression, which indicated that LTF plays an important role in the tumor microenvironment32. Here, CD8A is linked to differentiated thyroid carcinoma.