We transfected HEK293 cells either with Rnd1 encoding plasmid (pCMV-Flag-Rnd1) or vector backbone (pCMV-Flag-6c) and subsequently infected by NDV (GFP-tagged) and finally analysed for viral load 24 h post-infection, the viral load was significantly reduced (~10 fold) as shown in Fig. 2A. Here, RND1 is linked to infection.