Generally, we did not observe strong evidence suggesting colocalization between blood glucose and AD within the 2 gene regions for sulfonylureas (probability for sharing 1 common causal variant: 2.5% in KCNJ11 and 3.9% in ABCC8); however, when looking into the regional association plots (eFigure 3, links.lww.com/WNL/C91), a trend of colocalization was noted. The gene discussed is ABCC8; the disease is Alzheimer disease.