Very potent growth inhibition wasobserved in 14-day proliferative assays of BCL6 dependent DLBCL celllines, HT, Karpas 422, SU-DHL-4, and OCI-Ly1 but was not seen in theBCL6 low-expressing cell line OCI-Ly3. The gene discussed is CD8B; the disease is diffuse large B-cell lymphoma.