ESR1 and breast cancer: This seems to be particularly relevant as (i) our analysis of the METRABRIC database also supports that NBC are luminal p53 WT tumors and (ii) NBC have been reported to express the ER and to be eventually p53 WT and to be classified in the luminal breast cancer subtype according to the literature (Inno et al., 2016; Gallo et al., 2020; Marchiò et al., 2017).