The results demonstrated that more apical release of virus progeny was detected from the HAE-ALI expressing the mCherry control at the early phase of infection, and starting from 6 dpi, the Ku70-β-barrel, RPA70-AB expressing HAE-ALI decreased apical virus release at 2–3 logs less than that from the mCherry-expressing control (Fig 12C). This evidence concerns the gene XRCC6 and infection.