CXCL9 and vitiligo: Here, we combine MPM in vivo imaging of stable vitiligo patients and various scRNA-Seq analyses to demonstrate that a small subpopulation of stress keratinocytes in the basal/parabasal layer exhibit a unique signature — energy utilization preferences for OxPhos, expression of stress keratins, alarmins, and CXCL9/10 and diminished WNT signaling — and could drive the persistence of white patches in vitiligo.